(1S,2S)-trans-1,2-Diaminocyclohexane

(1S,2S)-Cyclohexane-1,2-diamine
CAS Number
21439-79-0
PubChem
Molecular Formula
C6H16N2
Molecular Weight
116.2 g/mol
Chiral Ligands Catalysts
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(1S,2S)-trans-1,2-Diaminocyclohexane (DACH) is a versatile chiral diamine ligand used to construct Jacobsen’s salen ligands, Noyori’s Ru(II) TsDPEN complexes, and numerous C2-symmetric catalysts for asymmetric hydrogenation, transfer hydrogenation, and epoxidation.

Applications

  • Salen ligand precursor (Jacobsen)
  • TsDPEN-type Ru(II) catalysts (Noyori)
  • Asymmetric transfer hydrogenation
  • Phase-transfer catalyst design

Specifications

Property Value
CAS 21439-79-0
Molecular Formula C6H16N2
Molecular Weight 116.20 g/mol
Purity >99%
Optical Rotation [α]D -26° (c 1, CHCl3)

Features

  • Cost-effective chiral building block
  • Rigid trans-cyclohexane scaffold
  • Modular derivatization to salen, TsDPEN
  • Excellent C2-symmetric design

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