Organic Chemistry Molecular Structure Background
SMALL-MOLECULE SYNTHESIS PLATFORM

Small-Molecule Synthesis, Designed for Scale

Precision synthesis of pharmaceutical intermediates, chiral catalysts, and specialty chemicals with process-oriented development and ISO-aligned quality control

Explore Products Request Quote
Scientific Leadership

Chief Scientist

Chief Scientist

Ph.D. | Small-Molecule Synthesis and Process Chemistry

Leads route scouting, chiral technology evaluation, and scale-up readiness decisions for complex small-molecule programs.

"Our synthesis strategy prioritizes route robustness, impurity control, and scalable execution."

Core Focus

Route Design Chiral Methodology Process Transfer

Decision Lens

Bench data translated into scalable route decisions.

Emphasis on route robustness, analytical clarity, and transfer readiness from discovery support to pilot-scale execution.

Our Specialized Services

Leveraging decades of expertise in synthetic chemistry and rigorous quality control processes

Custom Synthesis

Bespoke synthesis of compounds with precise specifications, from initial concept through production-scale manufacturing

From gram to kilogram scale ->

Scale-Up Production

Seamless scaling with consistent quality and reproducibility across pilot, pre-commercial, and commercial production phases

Reliable scale-up expertise ->

Quality Assurance

ISO-certified laboratories with comprehensive analytical documentation, CoA, and full traceability for regulatory compliance

Complete documentation ->

Featured Products

Highly refined chemical compounds engineered to precise specifications

Chiral Ligands

(R,R)-DACH-Phenyl Trost Ligand

IUPAC: (1R,2R)-N1,N2-Bis(2-diphenylphosphinobenzylidene)cyclohexane-1,2-diamine
CAS 138517-61-0
Formula C42H44N2O2
View Details ->
Chiral Catalysts

(R,R)-TsDPEN

IUPAC: N-((1R,2R)-2-Amino-1,2-diphenylethyl)-4-methylbenzenesulfonamide
CAS 167316-28-1
Formula C21H24N2O2S
View Details ->
Chiral Catalysts

(R)-2-Methyl-CBS-oxazaborolidine

IUPAC: (4R)-3,4-Dimethyl-2-phenyl-1,3,2-oxazaborolidine
CAS 112022-83-0
Formula C10H14BNO
View Details ->
Chiral Ligands

(R)-BINAP

IUPAC: (R)-(+)-1,1'-binaphthyl-2,2'-diyl bis(diphenylphosphine)
CAS 76189-55-4
Formula C44H32P2
View Details ->
Chiral Catalysts

(R)-BINAP-Ru(II) Dichloride

IUPAC: Dichloro[(R)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II)
CAS 132314-09-9
Formula C44H32Cl2P2Ru
View Details ->
Chiral Ligands

(R)-BINOL

IUPAC: (R)-(+)-1,1'-Bi-2-naphthol
CAS 18531-94-7
Formula C20H14O2
View Details ->
Chiral Catalysts

(S,S)-Jacobsen's Catalyst

IUPAC: (S,S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(III) chloride
CAS 138124-32-0
Formula C36H52ClMnN2O2
View Details ->
Chiral Catalysts

(S,S)-TsDPEN

IUPAC: N-((1S,2S)-2-Amino-1,2-diphenylethyl)-4-methylbenzenesulfonamide
CAS 167316-27-0
Formula C21H24N2O2S
View Details ->
Chiral Catalysts

(S)-2-Methyl-CBS-oxazaborolidine

IUPAC: (4S)-3,4-Dimethyl-2-phenyl-1,3,2-oxazaborolidine
CAS 112022-81-8
Formula C10H14BNO
View Details ->
Chiral Ligands

(S)-BINAP

IUPAC: (S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl
CAS 76189-56-5
Formula C44H32P2
View Details ->
Chiral Catalysts

(S)-BINAP-Ru(II) Dichloride

IUPAC: Dichloro[(S)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II)
CAS 132314-10-2
Formula C44H32Cl2P2Ru
View Details ->
Chiral Ligands

(S)-BINOL

IUPAC: (S)-(-)-1,1'-Bi-2-naphthol
CAS 18531-99-2
Formula C20H14O2
View Details ->
Chiral Catalysts

(S)-Jørgensen-Hayashi Catalyst

IUPAC: (S)-2-(Diphenyl(trimethylsilyloxy)methyl)pyrrolidine
CAS 1185498-18-9
Formula C20H27NOSi
View Details ->
Chiral Catalysts

(S)-MacMillan Imidazolidinone Catalyst

IUPAC: (2S,5S)-5-Benzyl-2-tert-butyl-3-methylimidazolidin-4-one
CAS 864237-25-4
Formula C13H23NO
View Details ->
Chiral Ligands

(S)-SEGPHOS

IUPAC: (S)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole
CAS 866081-54-1
Formula C38H28O4P2
View Details ->
Chiral Ligands

(S)-SPINOL

IUPAC: (S)-(-)-1,1'-Spirobiindane-7,7'-diol
CAS 144013-93-2
Formula C21H14O2
View Details ->
Chiral Ligands

(S)-t-Bu-BOX

IUPAC: (S)-2,2'-Isopropylidenebis[(4S)-4-tert-butyl-2-oxazoline]
CAS 200938-56-4
Formula C14H24N2O2
View Details ->
Chiral Catalysts

(S)-TRIP BINOL Phosphoric Acid

IUPAC: (S)-3,3'-Bis(2,4,6-triisopropylphenyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate
CAS 1190300-26-9
Formula C50H49O4P
View Details ->
Chiral Catalysts

[(R,R)-TsDPEN]Ru(p-cymene)Cl₂

IUPAC: Dichloro[(R,R)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine](p-cymene)ruthenium(II)
CAS 192139-92-7
Formula C31H34Cl2N2O2RuS
View Details ->
Chiral Catalysts

[(S,S)-TsDPEN]Ru(p-cymene)Cl₂

IUPAC: Dichloro[(S,S)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine](p-cymene)ruthenium(II)
CAS 192139-90-5
Formula C31H34Cl2N2O2RuS
View Details ->
Ionic Liquids

1-Ethyl-3-methylimidazolium Bromide

IUPAC: 1-ethyl-3-methylimidazolium bromide
CAS 65039-08-9
Formula C6H11BrN2
View Details ->
Amino Acids

BOC-L-tert-Leucine

IUPAC: N-(tert-butoxycarbonyl)-L-tert-leucine
CAS 157546-38-0
Formula C11H21NO4
View Details ->
Catalysts

Grubbs 2nd Generation Catalyst

IUPAC: [1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium(II)
CAS 246047-72-3
Formula C46H65Cl2N2PRu
View Details ->
Catalysts

Hoveyda-Grubbs 2nd Generation Catalyst

IUPAC: [1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(o-isopropoxyphenylmethylene)ruthenium(II)
CAS 301224-40-8
Formula C31H38Cl2N2ORu
View Details ->
Catalyst Precursors

IPr·HCl

IUPAC: 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride
CAS 250249-75-3
Formula C27H33ClN2
View Details ->
Catalyst Ligands

SPhos

IUPAC: 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
CAS 657408-07-6
Formula C24H25O2P
View Details ->
Catalyst Ligands

Xantphos

IUPAC: 4,5-Bis(diphenylphosphino)-9,9-dimethylxanthene
CAS 161265-03-8
Formula C39H32OP2
View Details ->
Catalyst Ligands

XPhos

IUPAC: 2-Dicyclohexylphosphino-2',4',6'-triisopropylbiphenyl
CAS 564483-18-7
Formula C24H35P
View Details ->

Technical Documentation

Comprehensive analytical reports, specifications, and compliance documentation

Technical

Rhodium-Catalyzed Asymmetric Hydrogenation of Enamides and Dehydroamino Acids

Rhodium-catalyzed asymmetric hydrogenation is the most mature and industrially deployed of all enantioselective …

Jun 25, 2026 Read ->
Technical

Ruthenium (BINAP)(Diamine) Catalysts for Asymmetric Hydrogenation of Aryl Ketones

While first-generation (BINAP)RuCl₂ catalysts excel at β-keto esters, they give poor enantioselectivity on …

Jun 20, 2026 Read ->
Technical

Asymmetric Transfer Hydrogenation with Noyori–Ikariya Ru-TsDPEN Catalysts

Asymmetric transfer hydrogenation (ATH) is one of the most operationally simple methods for reducing prochiral ketones …

Jun 15, 2026 Read ->
Technical

Palladium-Catalyzed Enantioselective Cross-Coupling: Atroposelective Suzuki and Asymmetric Heck

While most palladium cross-coupling uses achiral phosphines, a growing family of enantioselective Pd-catalyzed reactions …

Jun 12, 2026 Read ->
View All Documents

Ready to Start Your Project?

Connect with our expert team to discuss your synthesis requirements and receive a detailed project proposal

Request Quote Browse Products