(R)-PROPHOS

(R)-(+)-1,2-Bis(diphenylphosphino)propane
CAS Number
71497-64-6
PubChem
Molecular Formula
C25H24P2
Molecular Weight
386.4 g/mol
Chiral Ligands Catalysts
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(R)-PROPHOS is the enantiomeric form of (S)-PROPHOS, providing complementary stereocontrol in rhodium- and palladium-catalyzed asymmetric transformations.

Applications

  • Asymmetric hydrogenation of enamides
  • Enantioselective hydroformylation
  • Asymmetric allylic alkylation
  • Synthesis of chiral amines and alcohols

Specifications

Property Value
CAS 71497-64-6
Molecular Formula C25H24P2
Molecular Weight 386.40 g/mol
Purity >99%
Optical Rotation [α]D +18° (c 1, CHCl3)

Features

  • Mirror-image enantioselectivity to (S)-form
  • Compatible with Rh, Pd, and Ru
  • Robust under catalytic conditions
  • Industrially scalable

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