(R)-SIPHOS

(R)-(+)-7,7'-Bis(diarylphosphoramidite)-1,1'-spirobiindane
CAS Number
468617-23-4
PubChem
Molecular Formula
C33H26NO3P
Molecular Weight
515.54 g/mol
Chiral Ligands Catalysts
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(R)-SIPHOS is the enantiomeric form of (S)-SIPHOS, providing complementary stereochemistry in rhodium- and palladium-catalyzed asymmetric transformations based on the SPINOL scaffold.

Applications

  • Asymmetric hydrogenation of dehydroamino acids (Rh)
  • Enantioselective hydrogenation of enamides
  • Palladium-catalyzed allylic alkylation
  • Asymmetric hydrosilylation of olefins

Specifications

Property Value
CAS 468617-23-4
Molecular Formula C33H26NO3P
Molecular Weight 515.54 g/mol
Purity >99%
Appearance White to off-white solid

Features

  • Mirror-image enantioselectivity to (S)-SIPHOS
  • Rigid spiro phosphoramidite scaffold
  • Robust performance in hydrogenation
  • Industrial-scale production available

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