(R)-t-Bu-BOX

(R)-2,2'-Isopropylidenebis[(4R)-4-tert-butyl-2-oxazoline]
CAS Number
200938-57-5
PubChem
Molecular Formula
C14H24N2O2
Molecular Weight
252.35 g/mol
Chiral Ligands Catalysts
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(R)-t-Bu-BOX is the enantiomeric form of (S)-t-Bu-BOX, providing complementary stereochemical control in copper- and zinc-catalyzed asymmetric transformations including Diels-Alder, Henry, and cyclopropanation reactions.

Applications

  • Asymmetric Diels-Alder reactions (Cu)
  • Enantioselective Henry reactions (Cu)
  • Asymmetric Mukaiyama aldol reactions
  • Asymmetric cyclopropanation

Specifications

Property Value
CAS 200938-57-5
Molecular Formula C14H24N2O2
Molecular Weight 252.35 g/mol
Purity >99%
Optical Rotation [α]D +120° (c 1, CHCl3)

Features

  • Mirror-image enantioselectivity to (S)-form
  • C2-symmetric bisoxazoline scaffold
  • Versatile across Lewis acid metals
  • Robust catalytic performance

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