(S)-CHIRAPHOS

(2S,3S)-Bis(diphenylphosphino)butane
CAS Number
64896-28-2
PubChem
Molecular Formula
C26H24P2
Molecular Weight
398.41 g/mol
Chiral Ligands Catalysts
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(S)-CHIRAPHOS is a chiral C2-symmetric bidentate phosphine ligand featuring stereocenters on the carbon backbone. It forms highly enantioselective rhodium complexes for asymmetric hydrogenation of dehydroamino acids and related substrates.

Applications

  • Asymmetric hydrogenation of dehydroamino acids (Rh)
  • Enantioselective hydrogenation of enamides
  • Asymmetric hydroformylation (Rh)
  • Synthesis of chiral α-amino acids

Specifications

Property Value
CAS 64896-28-2
Molecular Formula C26H24P2
Molecular Weight 398.41 g/mol
Purity >99%
Optical Rotation [α]D -19° (c 1, CHCl3)

Features

  • C2-symmetric design
  • Carbon-based stereocenters
  • High air stability
  • Cost-effective vs. BINAP for some applications

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