(S,S)-DACH-Phenyl Trost Ligand

(1S,2S)-N1,N2-Bis(2-diphenylphosphinobenzylidene)cyclohexane-1,2-diamine
CAS Number
138517-66-5
PubChem
Molecular Formula
C42H44N2O2
Molecular Weight
612.81 g/mol
Chiral Ligands Catalysts
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(S,S)-DACH-phenyl Trost ligand is the enantiomeric form of the privileged Trost diphosphine ligand, providing complementary stereochemical outcomes in palladium-catalyzed asymmetric allylic alkylation reactions.

Applications

  • Palladium-catalyzed allylic alkylation
  • Enantioselective allylic amination
  • Synthesis of (S)-configured chiral building blocks
  • API intermediate production

Specifications

Property Value
CAS 138517-66-5
Molecular Formula C42H44N2O2
Molecular Weight 612.81 g/mol
Purity ≥99%
Appearance Yellow crystalline solid

Features

  • Mirror-image enantioselectivity to (R,R)-form
  • Validated for pharmaceutical manufacturing
  • Robust allylic substitution performance
  • Excellent reproducibility

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