IMes·HCl

1,3-Bis(2,4,6-trimethylphenyl)imidazolium chloride
CAS Number
141556-45-8
PubChem
Molecular Formula
C21H25ClN2
Molecular Weight
340.89 g/mol
Catalyst Precursors Catalysts
Request Quote

IMes·HCl (1,3-bis(2,4,6-trimethylphenyl)imidazolium chloride) is the foundational N-heterocyclic carbene (NHC) precatalyst developed by Arduengo. Deprotonation generates the IMes carbene, a strong σ-donor ligand used in palladium, nickel, ruthenium, and gold catalysis.

Applications

  • Suzuki-Miyaura cross-coupling (Pd/IMes)
  • Olefin metathesis (Ru/IMes, second-generation Grubbs)
  • Hydrosilylation and hydroamination
  • Gold-catalyzed alkyne activation

Specifications

Property Value
CAS 141556-45-8
Molecular Formula C21H25ClN2
Molecular Weight 340.89 g/mol
Purity >99%
Appearance White to off-white solid

Features

  • Strong σ-donor carbene precursor
  • Air- and moisture-stable salt
  • Cost-effective for large-scale use
  • Versatile across transition metals

Related Products

Catalysts

Grubbs 2nd Generation Catalyst

[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)ruthenium(II)
CAS: 246047-72-3
Formula: C46H65Cl2N2PRu
MW: 848.97 g/mol
Catalysts Catalyst Precursors
View Details ->
Catalysts

Hoveyda-Grubbs 2nd Generation Catalyst

[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(o-isopropoxyphenylmethylene)ruthenium(II)
CAS: 301224-40-8
Formula: C31H38Cl2N2ORu
MW: 626.61 g/mol
Catalysts Catalyst Precursors
View Details ->
Catalyst Precursors

IPr·HCl

1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride
CAS: 250249-75-3
Formula: C27H33ClN2
MW: 425.01 g/mol
Catalyst Precursors Catalysts
View Details ->
Chiral Ligands

(1R,2R)-trans-1,2-Diaminocyclohexane

(1R,2R)-Cyclohexane-1,2-diamine
CAS: 20439-47-8
Formula: C6H16N2
MW: 116.2 g/mol
Chiral Ligands Catalysts
View Details ->
Chiral Ligands

(1S,2S)-trans-1,2-Diaminocyclohexane

(1S,2S)-Cyclohexane-1,2-diamine
CAS: 21439-79-0
Formula: C6H16N2
MW: 116.2 g/mol
Chiral Ligands Catalysts
View Details ->
Chiral Ligands

(R,R)-DACH-Phenyl Trost Ligand

(1R,2R)-N1,N2-Bis(2-diphenylphosphinobenzylidene)cyclohexane-1,2-diamine
CAS: 138517-61-0
Formula: C42H44N2O2
MW: 612.81 g/mol
Chiral Ligands Catalysts
View Details ->