(R,R)-Jacobsen's Catalyst

(R,R)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(III) chloride
CAS Number
135620-04-1
PubChem
Molecular Formula
C36H52ClMnN2O2
Molecular Weight
635.25 g/mol
Chiral Catalysts Catalysts
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(R,R)-Jacobsen’s catalyst is the enantiomeric Mn(III)-salen complex, providing access to opposite enantiomers in the asymmetric epoxidation of cis-olefins. It is essential for processes requiring (R)-configured epoxide intermediates.

Applications

  • Asymmetric epoxidation of cis-olefins
  • Synthesis of (R)-configured epoxides
  • Kinetic resolution of racemic epoxides
  • Drug intermediate manufacturing

Specifications

Property Value
CAS 135620-04-1
Molecular Formula C36H52ClMnN2O2
Molecular Weight 635.25 g/mol
Purity >98%
Appearance Brown to dark brown solid

Features

  • Mirror-image enantioselectivity to (S,S)-form
  • Compatible with aqueous NaOCl
  • Excellent catalyst turnover
  • Suitable for cGMP production

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