(R,R)-TsDPEN

N-((1R,2R)-2-Amino-1,2-diphenylethyl)-4-methylbenzenesulfonamide
CAS Number
167316-28-1
PubChem
Molecular Formula
C21H24N2O2S
Molecular Weight
368.49 g/mol
Chiral Catalysts Catalysts
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(R,R)-TsDPEN is the enantiomeric form of (S,S)-TsDPEN, providing complementary stereochemical outcomes in ruthenium-catalyzed asymmetric transfer hydrogenation of prochiral ketones and imines. It is the ligand of choice for producing (R)-configured chiral alcohols and amines.

Applications

  • Asymmetric transfer hydrogenation of ketones (Ru)
  • ATH of imines to (R)-chiral amines
  • Pharmaceutical intermediate production
  • Synthesis of (R)-1-phenylethanol derivatives

Specifications

Property Value
CAS 167316-28-1
Molecular Formula C21H24N2O2S
Molecular Weight 368.49 g/mol
Purity >99%
Optical Rotation [α]D +180° (c 1, MeOH)

Features

  • Mirror-image enantioselectivity to (S,S)-form
  • Industrial-scale validated catalyst
  • Compatible with green hydrogen sources
  • Robust performance in aqueous media

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