(S,S)-Jacobsen's Catalyst

(S,S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(III) chloride
CAS Number
138124-32-0
PubChem
Molecular Formula
C36H52ClMnN2O2
Molecular Weight
635.25 g/mol
Chiral Catalysts Catalysts
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(S,S)-Jacobsen’s catalyst is the chiral Mn(III)-salen complex developed by Eric Jacobsen for the asymmetric epoxidation of unfunctionalized cis-olefins. It remains one of the most reliable methods for accessing enantioenriched epoxides.

Applications

  • Asymmetric epoxidation of cis-olefins
  • Enantioselective ring-opening of epoxides
  • Synthesis of chiral 1,2-diols
  • Pharmaceutical intermediate production

Specifications

Property Value
CAS 138124-32-0
Molecular Formula C36H52ClMnN2O2
Molecular Weight 635.25 g/mol
Purity >98%
Appearance Brown to dark brown solid

Features

  • High enantioselectivity for cis-olefins
  • Mild oxidant (NaOCl) compatibility
  • Robust across diverse substrate classes
  • Scalable to industrial processes

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Formula: C36H52ClMnN2O2
MW: 635.25 g/mol
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