TADDOL

4 articles

Titanium-Catalyzed Asymmetric Lewis Acid Catalysis: TADDOLate and BINOLate Complexes

Titanium is the dominant Lewis acid metal for asymmetric catalysis, owing to its well-defined octahedral coordination geometry, tunable ligand sphere, and compatibility with a wide …

2026-05-26

Metal Catalysis, Science 8 tags

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TADDOL and DIOP Ligands in Asymmetric Titanium and Rhodium Catalysis

TADDOL (α,α,α’,α’-tetraaryl-1,3-dioxolane-4,5-dimethanol) and DIOP (2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane) are two foundational chiral …

2026-02-20

Methodology, Science 7 tags

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(R)-TADDOL

(R)-TADDOL is the enantiomeric form of (S)-TADDOL, providing complementary stereochemistry in Lewis acid-catalyzed asymmetric cycloadditions and aldol reactions. The …

0001-01-01

Chiral Ligands, Catalysts 4 tags

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(S)-TADDOL

(S)-TADDOL is a chiral diol ligand developed by Seebach, featuring a rigid C2-symmetric 1,3-dioxolane backbone. It forms powerful chiral Lewis acid catalysts with titanium, boron, …

0001-01-01

Chiral Ligands, Catalysts 4 tags

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