Bisoxazoline

3 articles

BOX Ligands in Lewis Acid Catalysis: t-Bu-BOX and Asymmetric Cycloadditions

Bisoxazoline (BOX) ligands, developed in the 1990s by Pfaltz, Ghosh, and Evans, are the dominant chiral scaffolds for Lewis acid-catalyzed asymmetric reactions. The …

2026-02-28

Methodology, Science 6 tags

Read ->

Taxonomy

(R)-t-Bu-BOX

(R)-t-Bu-BOX is the enantiomeric form of (S)-t-Bu-BOX, providing complementary stereochemical control in copper- and zinc-catalyzed asymmetric transformations including …

0001-01-01

Chiral Ligands, Catalysts 4 tags

Read ->

Taxonomy

(S)-t-Bu-BOX

(S)-t-Bu-BOX is a chiral C2-symmetric bisoxazoline (BOX) ligand featuring tert-butyl substituents that create a sterically demanding chiral pocket. It forms highly enantioselective …

0001-01-01

Chiral Ligands, Catalysts 4 tags

Read ->

Back to All Documents